CD90 antibody
Quick Overview for CD90 antibody (ABIN1837671)
Target
See all CD90 (THY1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- CD90 is also known as Thy-1 antigen and a member of the immunoglobulin superfamily. It may contribute to inhibition of proliferation/differentiation of hematopoietic stem cells and neuron memory formation in the CNS. It consists of a single Ig domain (112 amino acids, 25-35 kD) inserted into the cell membrane via a GPI anchor. Expressed by hematopoietic stem cells and neurons in all species studied. Its highly expressed in connective tissue and various fibroblast and stromal cell lines, expressed on all thymocytes and peripheral T cells in mice, but in humans expressed only on small % fetal thymocytes, 10-40 % of CD34+ cells in bone marrow, and <1 % of CD3+CD4+ lymphocytes in peripheral circulation. It is also expressed by human lymph node HEV endothelium but not other endothelia. Lastly, it is expressed by a limited number of lymphoblastoid and leukemic cell lines.
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Purification
- Purified
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Immunogen
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T cell lymphoma cells.
Type of Immunogen: Cells -
Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 0.05 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Store at 4°C.
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- CD90 (THY1)
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Alternative Name
- THY1 / CD90
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Background
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Name/Gene ID: THY1
Synonyms: THY1, CD90 antigen, CD90, CDw90, Thy-1 antigen, Thy-1 T-cell antigen, Thy-1, Thy-1 cell surface antigen, Thy-1 membrane glycoprotein -
Gene ID
- 7070
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UniProt
- P04216
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Pathways
- Cell-Cell Junction Organization
Target
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